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Fernando Schmitt Selected Research

Cadherins (E-Cadherin)

12/2020P-cadherin induces anoikis-resistance of matrix-detached breast cancer cells by promoting pentose phosphate pathway and decreasing oxidative stress.
11/2020BR-BCSC Signature: The Cancer Stem Cell Profile Enriched in Brain Metastases that Predicts a Worse Prognosis in Lymph Node-Positive Breast Cancer.
11/2019S100P is a molecular determinant of E-cadherin function in gastric cancer.
1/2018Hereditary lobular breast cancer with an emphasis on E-cadherin genetic defect.
1/2017P-cadherin: a useful biomarker for axillary-based breast cancer decisions in the clinical practice.
10/2014The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype.
8/2014Fibromatosis-like metaplastic carcinoma of the breast has a claudin-low immunohistochemical phenotype.
2/2014P-cadherin signals through the laminin receptor α6β4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells.
4/2013P-cadherin functional role is dependent on E-cadherin cellular context: a proof of concept using the breast cancer model.
1/2013CCAAT/enhancer binding protein β (C/EBPβ) isoforms as transcriptional regulators of the pro-invasive CDH3/P-cadherin gene in human breast cancer cells.
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Fernando Schmitt Research Topics

Disease

67Neoplasms (Cancer)
05/2022 - 01/2002
66Breast Neoplasms (Breast Cancer)
01/2022 - 01/2002
18Carcinoma (Carcinomatosis)
05/2022 - 01/2002
7Neoplasm Metastasis (Metastasis)
03/2015 - 03/2009
5Lung Neoplasms (Lung Cancer)
01/2021 - 06/2012
5Carcinogenesis
10/2012 - 07/2004
4Triple Negative Breast Neoplasms
10/2020 - 07/2011
4Prostatic Neoplasms (Prostate Cancer)
09/2009 - 04/2008
3Stomach Neoplasms (Stomach Cancer)
11/2019 - 09/2009
3Hypoxia (Hypoxemia)
01/2018 - 01/2004
3Ductal Carcinoma
08/2013 - 01/2002
3Noninfiltrating Intraductal Carcinoma (DCIS)
08/2013 - 01/2002
2Disease Progression
12/2020 - 01/2019
2Acidosis
12/2020 - 10/2008
2Sarcoma (Soft Tissue Sarcoma)
01/2019 - 08/2017
2Lymphatic Metastasis
01/2017 - 07/2008
2Colorectal Neoplasms (Colorectal Cancer)
02/2008 - 02/2008
2Familial Breast Cancer
07/2007 - 06/2007
1Glioblastoma (Glioblastoma Multiforme)
02/2022
1Pleural Effusion (Pleural Effusions)
01/2022
1Residual Neoplasm
12/2020
1Brain Neoplasms (Brain Tumor)
11/2020
1Mesothelioma
11/2019
1Malignant Mesothelioma
11/2019
1Lymphoma (Lymphomas)
06/2019
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
06/2019
1Non-Hodgkin Lymphoma (Lymphosarcoma)
06/2019
1Neuroblastoma
08/2017
1Papillary Thyroid Cancer
05/2017

Drug/Important Bio-Agent (IBA)

28Cadherins (E-Cadherin)IBA
12/2020 - 01/2002
17Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2002
14Proteins (Proteins, Gene)FDA Link
01/2021 - 11/2004
11Phenobarbital (Luminal)FDA Link
04/2015 - 10/2005
10Estrogen ReceptorsIBA
01/2022 - 01/2002
8Biological ProductsIBA
12/2020 - 01/2002
7DNA (Deoxyribonucleic Acid)IBA
01/2022 - 07/2005
5Hormones (Hormone)IBA
01/2021 - 12/2005
5Lactic Acid (Lactate)FDA LinkGeneric
06/2019 - 06/2010
5ErbB Receptors (EGF Receptor)IBA
01/2019 - 10/2011
4AcidsIBA
02/2021 - 02/2008
4human ERBB2 proteinIBA
10/2020 - 07/2009
4ClaudinsIBA
08/2014 - 06/2012
4Protein Isoforms (Isoforms)IBA
01/2013 - 01/2007
3VimentinIBA
08/2014 - 01/2010
3Cell Adhesion MoleculesIBA
02/2014 - 01/2011
3Trastuzumab (Herceptin)FDA Link
01/2014 - 07/2009
3Transcription Factors (Transcription Factor)IBA
01/2013 - 01/2009
3Vitamin DFDA LinkGeneric
05/2012 - 10/2009
3Estrogen Receptor alphaIBA
07/2010 - 11/2004
3Fulvestrant (Faslodex)FDA Link
07/2010 - 01/2003
3Estrogens (Estrogen)FDA Link
08/2008 - 01/2002
2Doxorubicin (Adriamycin)FDA LinkGeneric
02/2021 - 12/2020
2Protons (Proton)IBA
02/2021 - 10/2008
2Nucleic AcidsIBA
07/2019 - 06/2011
2Glucose (Dextrose)FDA LinkGeneric
06/2019 - 01/2016
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2019 - 08/2017
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2015 - 09/2008
2MicroRNAs (MicroRNA)IBA
03/2015 - 01/2015
2AntibodiesIBA
01/2014 - 07/2007
2Androgen Receptors (Androgen Receptor)IBA
11/2013 - 02/2012
2EnzymesIBA
06/2013 - 01/2004
2Indicators and Reagents (Reagents)IBA
01/2013 - 01/2011
225-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA
05/2012 - 09/2010
2Keratin-5 (Keratin 5)IBA
10/2011 - 10/2005
2Progesterone Receptors (Progesterone Receptor)IBA
10/2011 - 07/2011
2Phosphotransferases (Kinase)IBA
08/2007 - 01/2005
1FurinIBA
05/2022
1Colloids (Colloid)IBA
01/2022
1SodiumIBA
02/2021
1Adenosine Triphosphatases (ATPase)IBA
02/2021
1Carbonic Anhydrases (Carbonic Anhydrase)IBA
02/2021
1Circulating Tumor DNAIBA
12/2020
1AntioxidantsIBA
12/2020
1Acetyl Coenzyme A (Acetyl-CoA)IBA
12/2020
1Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA
12/2020
1CatalaseIBA
12/2020
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2020
1Oxidoreductases (Dehydrogenase)IBA
12/2020
1Superoxides (Superoxide)IBA
12/2020
1Pyruvic Acid (Pyruvate)IBA
12/2020
1Epithelial Cell Adhesion MoleculeIBA
11/2020
1Genetic Markers (Genetic Marker)IBA
11/2019
1Claudin-4IBA
11/2019
1AZD3965IBA
06/2019
1SilverIBA
08/2017
1Cyclin D1IBA
04/2015
1Epidermal Growth Factor (EGF)IBA
03/2015
1synaptojaninIBA
01/2015
1LipidsIBA
01/2015
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2015
1CarcinogensIBA
01/2015
1Calcium-Binding ProteinsIBA
01/2015
1TOR Serine-Threonine KinasesIBA
11/2014

Therapy/Procedure

27Therapeutics
01/2022 - 01/2002
4Drug Therapy (Chemotherapy)
02/2021 - 06/2013
3Immunotherapy
02/2022 - 08/2008
3Precision Medicine
12/2020 - 11/2019
2Operative Surgical Procedures
01/2019 - 12/2005
2Mastectomy (Mammectomy)
01/2015 - 11/2009
1Neoadjuvant Therapy
12/2020